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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine



   barrett esophagus
  

Disease ID 169
Disease barrett esophagus
Definition
A condition with damage to the lining of the lower ESOPHAGUS resulting from chronic acid reflux (ESOPHAGITIS, REFLUX). Through the process of metaplasia, the squamous cells are replaced by a columnar epithelium with cells resembling those of the INTESTINE or the salmon-pink mucosa of the STOMACH. Barrett's columnar epithelium is a marker for severe reflux and precursor to ADENOCARCINOMA of the esophagus.
Synonym
barret syndrome
barrett esophagitis
barrett esophagus [disease/finding]
barrett metaplasia
barrett oesophagitis
barrett syndrome
barrett's esophagitis
barrett's esophagus
barrett's esophagus (diagnosis)
barrett's esophagus (disorder)
barrett's esophagus (disorder) [ambiguous]
barrett's oesophagitis
barrett's oesophagus
barrett's oesophagus (disorder)
barrett's syndrome
barretts esophagus
barretts syndrome
be
bo - barrett's esophagus
bo - barrett's oesophagus
cello
cello - columnar epithelial-lined lower esophagus
cello - columnar epithelial-lined lower oesophagus
cle
cle - columnar-lined esophagus
cle - columnar-lined oesophagus
columnar epithelial-lined lower esophagus
columnar epithelial-lined lower oesophagus
columnar-lined esophagus
columnar-lined oesophagus
endobrachyesophagus
endobrachyoesophagus
esophagus, barrett
esophagus, barrett's
esophagus, columnar-lined
gastric metaplasia of esophagus
gastric metaplasia of oesophagus
syndrome, barrett
syndrome, barrett's
OMIM
DOID
UMLS
C0004763
MeSH
SNOMED-CT
Comorbidity
UMLS | Disease | Sentences' Count(Total Sentences:45)
C0001418  |  adenocarcinoma  |  53
C0279628  |  esophageal adenocarcinoma  |  37
C0017168  |  esophageal reflux  |  13
C0017168  |  oesophageal reflux  |  13
C0017168  |  gastroesophageal reflux  |  10
C0017168  |  esophageal reflux disease  |  6
C0014859  |  esophageal cancer  |  6
C0017168  |  gastroesophageal reflux disease  |  6
C0279628  |  oesophageal adenocarcinoma  |  5
C0001418  |  adenocarcinomas  |  5
C0028754  |  obesity  |  5
C0014868  |  esophagitis  |  5
C0011847  |  diabetes  |  3
C0014869  |  reflux esophagitis  |  3
C0017168  |  gastro-oesophageal reflux  |  3
C0014867  |  esophageal varices  |  2
C0019291  |  hiatal hernia  |  2
C0002871  |  anemia  |  1
C0020459  |  hyperinsulinemia  |  1
C0341106  |  eosinophilic esophagitis  |  1
C0011860  |  type ii diabetes mellitus  |  1
C0003125  |  anorexia nervosa  |  1
C0017152  |  gastritis  |  1
C0009402  |  colorectal cancer  |  1
C0686619  |  lymph node metastases  |  1
C0152018  |  carcinoma of the esophagus  |  1
C0008350  |  gallstones  |  1
C0006142  |  breast cancer  |  1
C0022821  |  kyphosis  |  1
C0520679  |  obstructive sleep apnea  |  1
C0546837  |  esophageal cancers  |  1
C0162316  |  iron deficiency anemia  |  1
C0279628  |  adenocarcinoma of the esophagus  |  1
C0004096  |  asthma  |  1
C0017168  |  acid reflux  |  1
C0001430  |  adenoma  |  1
C0011849  |  diabetes mellitus  |  1
C0014867  |  oesophageal varices  |  1
C0013395  |  dyspepsia  |  1
C0011860  |  type ii diabetes  |  1
C0007113  |  rectal cancer  |  1
C0205698  |  undifferentiated carcinoma  |  1
C0037315  |  sleep apnea  |  1
C0948265  |  metabolic syndrome  |  1
C0004763  |  columnar-lined esophagus  |  1
Curated Gene
Entrez_id | Symbol | Resource(Total Genes:17)
5970  |  RELA  |  CTD_human
5468  |  PPARG  |  CTD_human
4170  |  MCL1  |  CTD_human
23373  |  CRTC1  |  GWASCAT
3082  |  HGF  |  CTD_human
3576  |  CXCL8  |  CTD_human
5743  |  PTGS2  |  CTD_human
1012  |  CDH13  |  CTD_human
6750  |  SST  |  CTD_human
8854  |  ALDH1A2  |  GWASCAT
2520  |  GAST  |  CTD_human
8856  |  NR1I2  |  CTD_human
51637  |  C14orf166  |  OMIM
56475  |  RPRM  |  CTD_human
6548  |  SLC9A1  |  CTD_human
81696  |  OR5V1  |  GWASCAT
1592  |  CYP26A1  |  CTD_human
Inferring Gene
Entrez_id | Symbol | Resource(Total Genes:16)
2944  |  GSTM1  |  CIPHER
4968  |  OGG1  |  CIPHER
6647  |  SOD1  |  CIPHER
5970  |  RELA  |  CTD_human
3082  |  HGF  |  CTD_human
1012  |  CDH13  |  CTD_human
6750  |  SST  |  CTD_human
3576  |  CXCL8  |  CTD_human
2520  |  GAST  |  CTD_human
8856  |  NR1I2  |  CTD_human
5743  |  PTGS2  |  CTD_human
56475  |  RPRM  |  CTD_human
6548  |  SLC9A1  |  CTD_human
1592  |  CYP26A1  |  CTD_human
5468  |  PPARG  |  CTD_human
4170  |  MCL1  |  CTD_human
Text Mined Gene
Entrez_id | Symbol | Score | Resource(Total Genes:90)
131  |  ADH7  |  1.04  |  DISEASES
9370  |  ADIPOQ  |  2.142  |  DISEASES
84740  |  AFAP1-AS1  |  1.658  |  DISEASES
23600  |  AMACR  |  2.206  |  DISEASES
338699  |  ANKRD42  |  2.361  |  DISEASES
51008  |  ASCC1  |  3.386  |  DISEASES
1822  |  ATN1  |  1.869  |  DISEASES
648  |  BMI1  |  1.158  |  DISEASES
54796  |  BNC2  |  1.524  |  DISEASES
56244  |  BTNL2  |  1.567  |  DISEASES
988  |  CDC5L  |  1.505  |  DISEASES
1029  |  CDKN2A  |  3.973  |  DISEASES
1045  |  CDX2  |  3.768  |  DISEASES
1052  |  CEBPD  |  1.975  |  DISEASES
9075  |  CLDN2  |  1.429  |  DISEASES
1366  |  CLDN7  |  1.445  |  DISEASES
81035  |  COLEC12  |  1.749  |  DISEASES
84701  |  COX4I2  |  1.316  |  DISEASES
341947  |  COX8C  |  2.975  |  DISEASES
1385  |  CREB1  |  1.579  |  DISEASES
23373  |  CRTC1  |  2.935  |  DISEASES
115908  |  CTHRC1  |  2.082  |  DISEASES
1499  |  CTNNB1  |  1.738  |  DISEASES
3491  |  CYR61  |  1.16  |  DISEASES
85443  |  DCLK3  |  1.398  |  DISEASES
9231  |  DLG5  |  1.037  |  DISEASES
79962  |  DNAJC22  |  3.483  |  DISEASES
30836  |  DNTTIP2  |  2.002  |  DISEASES
50506  |  DUOX2  |  1.065  |  DISEASES
1854  |  DUT  |  1.071  |  DISEASES
2070  |  EYA4  |  1.168  |  DISEASES
2246  |  FGF1  |  1.696  |  DISEASES
2272  |  FHIT  |  1.993  |  DISEASES
2520  |  GAST  |  2.468  |  DISEASES
2878  |  GPX3  |  1.15  |  DISEASES
2882  |  GPX7  |  2.862  |  DISEASES
2886  |  GRB7  |  1.684  |  DISEASES
9446  |  GSTO1  |  1.307  |  DISEASES
119391  |  GSTO2  |  1.225  |  DISEASES
2950  |  GSTP1  |  2.184  |  DISEASES
3055  |  HCK  |  1.109  |  DISEASES
3167  |  HMX2  |  1.46  |  DISEASES
3274  |  HRH2  |  2.605  |  DISEASES
170572  |  HTR3C  |  2.319  |  DISEASES
3486  |  IGFBP3  |  1.459  |  DISEASES
57611  |  ISLR2  |  2.672  |  DISEASES
9445  |  ITM2B  |  1.34  |  DISEASES
221037  |  JMJD1C  |  1.617  |  DISEASES
133746  |  JMY  |  2.115  |  DISEASES
102723508  |  KANTR  |  1.123  |  DISEASES
3855  |  KRT7  |  1.662  |  DISEASES
51520  |  LARS  |  2.404  |  DISEASES
83655  |  LINC00208  |  3.242  |  DISEASES
114614  |  MIR155HG  |  1.345  |  DISEASES
25821  |  MTO1  |  1.314  |  DISEASES
4583  |  MUC2  |  2.47  |  DISEASES
4586  |  MUC5AC  |  1.581  |  DISEASES
4588  |  MUC6  |  2.184  |  DISEASES
4599  |  MX1  |  1.224  |  DISEASES
4609  |  MYC  |  2.188  |  DISEASES
4650  |  MYO9B  |  1.301  |  DISEASES
4720  |  NDUFS2  |  1.442  |  DISEASES
51199  |  NIN  |  1.905  |  DISEASES
79400  |  NOX5  |  2.519  |  DISEASES
9971  |  NR1H4  |  1.11  |  DISEASES
93034  |  NT5C1B  |  1.232  |  DISEASES
54681  |  P4HTM  |  2.002  |  DISEASES
27328  |  PCDH11X  |  1.234  |  DISEASES
80012  |  PHC3  |  1.127  |  DISEASES
26147  |  PHF19  |  2.047  |  DISEASES
51230  |  PHF20  |  1.175  |  DISEASES
23533  |  PIK3R5  |  1.552  |  DISEASES
56937  |  PMEPA1  |  1.393  |  DISEASES
5743  |  PTGS2  |  3.744  |  DISEASES
5697  |  PYY  |  1.186  |  DISEASES
5983  |  RFC3  |  1.903  |  DISEASES
864  |  RUNX3  |  1.727  |  DISEASES
6279  |  S100A8  |  1.194  |  DISEASES
140885  |  SIRPA  |  2.392  |  DISEASES
1811  |  SLC26A3  |  1.285  |  DISEASES
4089  |  SMAD4  |  2.091  |  DISEASES
9306  |  SOCS6  |  1.055  |  DISEASES
79582  |  SPAG16  |  1.727  |  DISEASES
6942  |  TCF20  |  3.779  |  DISEASES
9623  |  TCL1B  |  1.65  |  DISEASES
7033  |  TFF3  |  1.061  |  DISEASES
11076  |  TPPP  |  1.241  |  DISEASES
10103  |  TSPAN1  |  1.327  |  DISEASES
147645  |  VSIG10L  |  2.858  |  DISEASES
51741  |  WWOX  |  3.946  |  DISEASES
Locus(Waiting for update.)
Disease ID 169
Disease barrett esophagus
Integrated Phenotype(Waiting for update.)
Text Mined Phenotype
HPO | Name | Sentences' Count(Total Phenotypes:30)
HP:0002664  |  Neoplasia  |  38
HP:0002020  |  Heartburn  |  22
HP:0030731  |  Carcinoma  |  7
HP:0001513  |  Obesity  |  5
HP:0100633  |  Inflammation of the esophagus  |  5
HP:0012743  |  Central obesity  |  2
HP:0100790  |  Hernia  |  2
HP:0002036  |  Hiatus hernia  |  2
HP:0012735  |  Coughing  |  1
HP:0000819  |  Diabetes mellitus  |  1
HP:0000842  |  Elevated insulin level  |  1
HP:0002870  |  Obstructive sleep apnea  |  1
HP:0005978  |  Noninsulin dependent diabetes mellitus  |  1
HP:0005263  |  Gastritis  |  1
HP:0003470  |  Inability to move  |  1
HP:0001903  |  Anemia  |  1
HP:0002189  |  Excessive daytime sleepiness  |  1
HP:0002808  |  Gibbus deformity  |  1
HP:0002099  |  Asthma  |  1
HP:0012622  |  Chronic kidney disease  |  1
HP:0005231  |  Chronic gastritis  |  1
HP:0001262  |  Somnolence  |  1
HP:0002282  |  Heterotopias  |  1
HP:0003002  |  Breast carcinoma  |  1
HP:0001891  |  Iron-deficiency anemia  |  1
HP:0001880  |  Eosinophilia  |  1
HP:0002039  |  Anorexia  |  1
HP:0001081  |  Gallstones  |  1
HP:0002104  |  Absence of spontaneous respiration  |  1
HP:0010535  |  Sleep apnea  |  1
Disease ID 169
Disease barrett esophagus
Manually Symptom
UMLS  | Name(Total Manually Symptoms:8)
C1608408  |  malignant transformation
C0279628  |  esophageal adenocarcinoma
C0152018  |  carcinoma of the esophagus
C0017168  |  gastroesophageal reflux
C0014866  |  esophageal narrowing
C0014858  |  esophageal dysmotility
C0001418  |  adenocarcinomas
C0001418  |  adenocarcinoma
Text Mined Symptom
UMLS | Name | Sentences' Count(Total Symptoms:19)
C0001418  |  adenocarcinoma  |  56
C0279628  |  esophageal adenocarcinoma  |  34
C0017168  |  gastroesophageal reflux  |  8
C0014859  |  esophageal cancer  |  6
C0001418  |  adenocarcinomas  |  5
C0878500  |  intraepithelial neoplasia  |  5
C0279628  |  oesophageal adenocarcinoma  |  5
C0028754  |  obesity  |  5
C1608408  |  malignant transformation  |  4
C0017168  |  gastro-oesophageal reflux  |  2
C0017168  |  gastroesophageal reflux disease  |  2
C0017168  |  acid reflux  |  1
C0940937  |  precancerous lesions  |  1
C0017152  |  gastritis  |  1
C0032927  |  premalignant condition  |  1
C0009402  |  colorectal cancer  |  1
C0279628  |  adenocarcinoma of the esophagus  |  1
C0744318  |  gastroesophageal reflux symptoms  |  1
C0008350  |  gallstones  |  1
Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)
Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)
All Snps(Total Genotypes:9)
snpId pubmedId geneId geneSymbol diseaseId sourceId sentence score Year geneSymbol_dbSNP CHROMOSOME POS REF ALT
rs104192262412179023373CRTC1umls:C0004763GWASCATA genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.0.1202714422013CRTC11918692362TG
rs13181158789102068ERCC2umls:C0004763BeFreeSignificantly reduced frequencies were seen for the XPD Lys751Gln homozygous variant genotype in patients with EADC (OR = 0.24; 95% CI = 0.07-0.88), and for the XRCC1 Arg399Gln homozygous variant genotype in patients with BE (OR = 0.38; 95% CI = 0.12-0.64) and GERD (OR = 0.29; 95% CI = 0.12-0.66).0.0002714422005ERCC2;KLC31945351661TA,G
rs25487158789107515XRCC1umls:C0004763BeFreeThe protective effect of the homozygous variant of XRCC1 Arg399Gln for GERD and BE suggests that base excision repair alterations may occur early in progression to EADC, likely in response to GERD-induced endogenous oxidative or inflammatory DNA damage.0.0002714422005XRCC11943551574TC
rs25487158789102068ERCC2umls:C0004763BeFreeSignificantly reduced frequencies were seen for the XPD Lys751Gln homozygous variant genotype in patients with EADC (OR = 0.24; 95% CI = 0.07-0.88), and for the XRCC1 Arg399Gln homozygous variant genotype in patients with BE (OR = 0.38; 95% CI = 0.12-0.64) and GERD (OR = 0.29; 95% CI = 0.12-0.66).0.0002714422005XRCC11943551574TC
rs3784262241217908854ALDH1A2umls:C0004763GWASCATA genome-wide association study identifies new susceptibility loci for esophageal adenocarcinoma and Barrett's esophagus.0.122013ALDH1A21557960908TC
rs386493716158789107515XRCC1umls:C0004763BeFreeThe protective effect of the homozygous variant of XRCC1 Arg399Gln for GERD and BE suggests that base excision repair alterations may occur early in progression to EADC, likely in response to GERD-induced endogenous oxidative or inflammatory DNA damage.0.0002714422005NANANANANA
rs386493716158789102068ERCC2umls:C0004763BeFreeSignificantly reduced frequencies were seen for the XPD Lys751Gln homozygous variant genotype in patients with EADC (OR = 0.24; 95% CI = 0.07-0.88), and for the XRCC1 Arg399Gln homozygous variant genotype in patients with BE (OR = 0.38; 95% CI = 0.12-0.64) and GERD (OR = 0.29; 95% CI = 0.12-0.66).0.0002714422005NANANANANA
rs6214204033543479IGF1umls:C0004763BeFreeIGF1 SNP rs6214 was associated with BE (adjusted P = .039).0.0026384742010IGF1;LOC10536994212102399791CT
rs92578092296100181696OR5V1umls:C0004763GWASCATCommon variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.0.122012OR5V1629388554AG
GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)
GWASdb Snp Trait(Total Genotypes:42)
CHR POS SNPID REF ALT ORI_SNPID PMID P_VALUE P_VALUE_TEXT OR/BETA CI95_TEXT GWAS_INITIAL_SAMPLE_SIZE SUB_POPULATION SUPER_POPULATION GWAS_TRAIT HPO_ID HPO_TERM DO_ID DO_TERM MESH_ID MESH_TERM EFO_ID EFO_TERM DOLITE_TERM RISK_ALLELE PUBLICATION_TYPE AA GENE_SYMBOL TYPE REFGENE
17083719rs17030152TCrs17030152241217903.46E-04NA1.14[1.06-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs17030152-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
156786595rs3005897CTrs3005897241217903.78E-04NA1.14[1.05-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs3005897-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
331847360rs4611855TCrs4611855241217901.97E-04NA1.12[1.06-1.20]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs4611855-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
370928930rs2687201ACrs2687201241217902.00E-06NA1.18[1.10-1.26]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs2687201-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
370959438rs9837992GArs9837992241217901.00E-04NA1.14[1.07-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs9837992-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
3134599236rs7646638TCrs7646638241217901.42E-04NA1.28[1.12-1.45]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs7646638-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
3146402171rs1912785GArs1912785229610018.00E-06Circumference0.15[0.091-0.209] unit decreaseUp to 1,852 European ancestry cases; 5,172 European ancestry controlsEuropean(7024)ALL(7024)EUR(7024)ALL(7024)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
3167725349rs7632500AGrs7632500241217903.18E-05NA1.38[1.19-1.61]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs7632500-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
476081553rs1391010CTrs1391010241217908.48E-04NA1.15[1.06-1.25]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs1391010-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
476161222rs7681167AGrs7681167241217902.49E-04NA1.18[1.08-1.28]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs7681167-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
476163816rs6848890CTrs6848890241217903.31E-05NA1.2[1.11-1.32]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs6848890-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
476164287rs7691721CTrs7691721241217904.33E-04NA1.14[1.05-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs7691721-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
476169067rs1497205CTrs1497205241217902.86E-05NA1.16[1.09-1.25]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs1497205-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
476180442rs10021538AGrs10021538241217903.49E-04NA1.2[1.09-1.33]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs10021538-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
550634878rs6449586CTrs6449586241217901.00E-06NA1.16[1.10-1.25]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs6449586-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
629356331rs9257809AGrs9257809229610014.00E-09NA1.21[1.13-1.28] Up to 1,852 European ancestry cases; 5,172 European ancestry controlsEuropean(7024)ALL(7024)EUR(7024)ALL(7024)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs9257809-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
7153271877rs11771429CTrs11771429241217907.00E-06NA1.22[1.12-1.33]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs11771429-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
88713038rs4523255CTrs4523255241217902.46E-04NA1.13[1.06-1.21]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs4523255-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
864296883rs10112358CTrs10112358241217906.70E-04NA1.12[1.05-1.20]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs10112358-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
864334749rs1431594CTrs1431594241217909.76E-05NA1.14[1.07-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs1431594-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
986117401rs12552693TCrs12552693241217901.02E-05NA1.15[1.08-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs12552693-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
996716028rs11789015AGrs11789015241217905.00E-06NA1.18[1.10-1.27]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs11789015-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
996858411rs6479527GArs6479527241217904.74E-05NA1.14[1.08-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs6479527-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1036511451rs11010572GArs11010572241217903.56E-04NA1.17[1.07-1.27]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs11010572-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1088116479rs7904985GArs7904985241217906.00E-06NA1.17[1.10-1.26]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs7904985-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1213629381rs1531228CTrs1531228229610019.00E-06Circumference0.2[0.10-0.30] unit increaseUp to 1,852 European ancestry cases; 5,172 European ancestry controlsEuropean(7024)ALL(7024)EUR(7024)ALL(7024)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1353286950rs7330220CTrs7330220241217901.79E-04NA1.24[1.11-1.38]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs7330220-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1457297563rs12880053CArs12880053241217902.44E-04NA1.14[1.06-1.20]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs12880053-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
14102052775rs2895917CTrs2895917241217905.70E-05NA1.15[1.08-1.22]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs2895917-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1558253106rs3784262TCrs3784262241217904.00E-07NA1.18[1.11-1.25]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs3784262-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1586859476rs12901001AGrs12901001229610016.00E-06Circumference0.15[0.091-0.209] unit increaseUp to 1,852 European ancestry cases; 5,172 European ancestry controlsEuropean(7024)ALL(7024)EUR(7024)ALL(7024)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusNAResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1665980789rs254348AGrs254348241217901.15E-04NA1.14[1.06-1.20]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs254348-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1673125231rs9926271TCrs9926271241217902.73E-04NA1.59[1.23-2.04]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs9926271-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tC
1686400081rs3111601CTrs3111601241217904.24E-04NA1.13[1.05-1.20]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs3111601-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1686403118rs9936833CTrs9936833229610013.00E-10NA1.14[1.10-1.19] Up to 1,852 European ancestry cases; 5,172 European ancestry controlsEuropean(7024)ALL(7024)EUR(7024)ALL(7024)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs9936833-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tT
1686463695rs2178146TCrs2178146241217906.24E-04NA1.12[1.05-1.19]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs2178146-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1819654137rs4800353AGrs4800353241217901.64E-04NA1.19[1.09-1.32]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs4800353-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1829046606rs16961975GArs16961975241217902.63E-04NA1.72[1.29-2.30]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs16961975-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1918746593rs1991017TArs1991017241217909.22E-05NA1.14[1.07-1.21]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs1991017-TResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1918803172rs10419226TGrs10419226241217906.00E-08NA1.19[1.12-1.26]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs10419226-AResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
1918817903rs10423674CArs10423674241217901.92E-06NA1.18[1.10-1.25]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs10423674-GResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tA
1945242107rs2927438AGrs2927438241217901.33E-04NA1.16[1.08-1.25]2,416 European ancestry cases; 3,206 European ancestry controlsEuropean(5622)ALL(5622)EUR(5622)ALL(5622)Barrett's esophagusHPOID:0100580Barrett esophagusDOID:9206Barrett's esophagusD001471Barrett EsophagusEFOID:0000280Barrett's esophagusBarrett's esophagusrs2927438-CResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tG
Mapped by lexical matching(Total Items:0)
(Waiting for update.)
Mapped by homologous gene(Total Items:0)
(Waiting for update.)
Disease ID 169
Disease barrett esophagus
Case(Waiting for update.)